Research Projects Pharmacology

Dr. SHOMA MUKHERJEE

  1. A Comparative Study on the Effect of a Statin, Felodipine and Propranolol on Serum Lipid Profile, Creatinine and Blood Glucose Level of Rabbits. M.D Research Work 2002- 2005, Department of Pharmacology, Gauhati Medical College, Guwahati .Supervisor: Prof.  M. Lahkar.
  2. Co- supervisor – Ph.D. Degree in Pharmaceutical Medicine: June 2013 – 2015. Evaluation of oral bioavailability of Xolstat 20mg tablets (containing rosuvastatin calcium equivalent to rosuvastatin 20mg) of Ranbaxy Laboratories Limited in comparison with Crestor 20mg tablets (containing rosuvastatin calcium equivalent rosuvastatin 20mg) of IPR Pharmaceuticals Inc. and to assess the safety profile in healthy adult human subjects under fasting condition.
  3. Co-supervisor, M.Pharm Research Project, Faculty of Pharmacy, Jamia Hamdard, Nov 2015- 2017.To assess awareness of patients practicing Islam regarding lifestyle modification and medication alteration of antidiabetic during Ramadan: A survey. Supervisor: Prof. N. Saha.
  4. Co-supervisor, M.Pharm Research Project, Faculty of Pharmacy, Jamia Hamdard, 2016-2018. To assess knowledge, attitude and perception regarding antimicrobial use and resistance among the physicians, residents and final year medical students in a South Delhi teaching hospital. Supervisor: Prof. N. Saha.
  5. Effect of Phlorizin, a SGLT-1 inhibitor, alone and in combination with Metformin on glucose transport in everted sac model of rat intestine. STS- Project Co- Investigator (Reference ID: 2016- 02720). Principal Investigator: Prof. N Saha, Department of Pharmacology, HIMSR, 2016.
  6. Multicentric Global Clinical trial experience as Medical Monitor:
    1. Phase III Trial – Randomized, open –label study of xxx in subjects with Chemotherapy Induced Anaemia.
    2. Phase III Trial- Randomized, comparative, open –label study of intravenous xxx in patients with Non-Dialysis Dependent Chronic Kidney Disease and with Renal – Related Anaemia.
    3. A phase III, randomized, comparative, open- label study of intravenous xxx in inflammatory bowel disease subjects with iron deficiency anaemia
    4. Phase II Trial – To evaluate the safety, tolerability and efficacy of xxx to patients with colorectal adenocarcinoma previously untreated for metastatic disease.
    5. Phase IV Study – A multicenter, prospective, open label study of the safety and efficacy of xxx in Indian patients with symptomatic osteoarthritis of the knee (s) after initial and repeat treatment.
    6. Phase II Trial- Randomized, prospective, double blind, parallel group, multicenter study to determine safety and efficacy of xxx in treatment of Venous Leg Ulcer.Multicentric Global Clinical trial experience as Medical Monitor:
    7. Phase I/II/III – Pharmacokinetic and outcome study of xxx in subjects with Hemophilia B
    8. Phase II Trial – Randomized, comparative, open- label study of xxx in subjects with Stage 5 Chronic kidney Disease on Dialysis Therapy (CKD- 5D).
    9. Phase II Trial – A prospective, randomized, placebo- controlled study to evaluate the effect of xxx in the management of advanced cancer cervix
    10. Phase II Trial – Randomized, prospective, double blind, parallel group, multicenter study to determine safety and efficacy of xxx in Laparoscopic scar.
    11. Phase II Trial Randomized, prospective, double blind, parallel group, multicenter study to determine safety and efficacy of xxx in treatment of Diabetic Foot Ulcer.
    12. Phase III Trial – Study of xxx in previously treated pediatric subjects with Hemophilia B
  7. BA/BE Studies: Independently conducted around 300 healthy volunteer BA/BE studies as Principal Investigator & Senior Research Scientist from 2012 to Jan 2015.
  8. ICMR Funded Research Project Technically ApprovedJuly 2020 titled “A Study to Evaluate the Treatment Outcome, Safety, Plasma Concentration and Quality Of Life of Bedaquiline Treatment in North Indian Patients of MDR TB”.
  9. PI: Shoma Mukherjee, Co- PI: Prof. A. Ray
  10. Ongoing ICMR STS Project– Approved on June 2020 titled “A Drug Utilization Study and Safety Analysis of Psychotropic Drugs and its Impact on Quality of Life of Patients attending Psychiatry Outpatient Department of a Tertiary Care Teaching Hospital”  Reference ID : 2020-08743
  11. Guide: Dr. Shoma Mukherjee, Student: Arsh Arora

Dr. SANA REHMAN

  1. Co-Investigator in ICMR funded research project on “Pharmacological studies to evaluate the effects of Withania somnifera in experimental models of post-traumatic stress disorder (PTSD) and its mechanisms in rats” – from 2019 – 2021 (ongoing)
  2. Co-Supervisor in degree of master of science (medical physiology) hamdard institute of medical sciences and research jamia hamdard, new delhi (2020-2021). To study the analgesic & anti-inflammatory activity of l-arginine on albino mice. Guide-Dr. Alam.
  3. Co-Supervisor in degree of master of science (medical physiology) hamdard institute of medical sciences and research jamia hamdard, new delhi (2020-2021). To study the antidepressent effect of plant product on albino rat. Guide- Dr. Alam.